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Middle School Life Science Curriculum | NGSS Aligned | MS-LS1, LS2, LS3, LS4

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Description

This bundle includes all four complete, NGSS-aligned Middle School Life Science bundles—MS-PS1, MS-LS2, MS-LS3, and MS-LS4—curated to cover every performance expectation with engaging lessons, hands-on labs/engineering challenges, readings, activities, and organized teacher supports.

Why teachers love it

  • Truly comprehensive coverage of all MS-LS standards—no gaps, no guesswork.
  • No-prep & editable: ready-to-use PDFs, Word docs, and digital versions for seamless classroom integration.
  • Organized & easy to teach: a clearly described contents guide inside each bundle keeps everything at your fingertips.

My Promise to You

I know every classroom is different. If you purchase a resource and feel it is not the right fit for your students, contact me and I’ll provide 2x the amount you paid in store credit toward another resource in my store, so you can find something that better supports your students.


What’s Inside (by Standard)

MS-LS1: From Molecules to Organisms - Structures & Processes

Cells to systems, reproduction, growth, photosynthesis/respiration, and sensory receptors. Resources include complete lessons, lab/station activities, readings, Crash Course & Bill Nye worksheets, digital INB pages, vocabulary games, and projects.

MS-LS1-1:

  • What Makes Something Alive Lesson
  • Animal and Plant Cells Lesson
  • Viruses Reading
  • Crash Course Biology Why We Aren’t Just One Big Cell
  • Story Prompt Maya and the Remarkable World of Cells
  • Case Study - How Viruses Make Us Sick
  • Bill Nye Cells Video Worksheet
  • Unicellular Multicellular Organisms Digital Interactive Notebook Pages
  • Introduction to Cells Station Activity

MS-LS1-2:

  • Cell Membrane and Transport Lesson
  • Cellular Organelles Lesson
  • Card Matching Cell Organelles Card Matching Game
  • Cell Organelles - Scavenger Hunt
  • Cell Organization Digital Interactive Notebook Pages
  • Cells and Cell Organelles BINGO
  • Cells and Organelles Word Sprint Game
  • Cells and Organelles Word Search and Scramble
  • Cellular Organelles Structure and Function Lab Station Activity
  • Function of Cells Station Activity
  • Crash Course BIOLOGY A Tour of the Cell Video Worksheet
  • Diffusion Osmosis Through Cell Membrane Digital Interactive Notebook Pages
  • Science Story Prompt Tanisha and the Cell Explorer

MS-LS1-3:

  • Body Systems - Working Together to Keep You Alive! Lesson
  • Muscle Growth Reading
  • The Cardiovascular System Reading
  • Body Systems in Action! Project
  • Asthma and Asthma Attacks Reading
  • Crash Course Biology Animal Infrastructure
  • Human Body Systems Station Activity
  • The Circulatory System Digital Interactive Notebook Pages
  • The Digestive System Digital Interactive Notebook Pages
  • The Excretory System Digital Interactive Notebook Pages
  • The Muscular and Skeletal System Digital Interactive Notebook Pages
  • The Nervous System Digital Interactive Notebook Pages
  • The Respiratory System Digital Interactive Notebook Pages

MS-LS1-4:

  • How Plants and Animals Reproduce Lesson
  • Plant Reproduction Lesson
  • Animal and Plant Adaptations Station Activity
  • Crash Course Video Worksheet Sexual and Asexual Reproduction
  • Why Bees Are Important Reading

MS-LS1-5:

  • Why Do Organisms Grow Differently? Lesson
  • Genetic Technologies and Gene Therapy Introduction Lesson
  • Genetic and Environmental Factors and Growth Station Activity
  • Human Impact on Ecosystems Lab Experiment Ecobottles
  • Human Impact on Ecosystems Assignment
  • What Affects Growth - Exploring Environmental and Genetic Factors Through Data Activity
  • Crash Course Biology Video Worksheet Nature Nurture Not That Simple
  • Crash Course Biology Video Worksheet How Genes Express Themselves
  • Genetically Modified Organisms Reading
  • Genetics and Gene Therapy Reading
  • Physical Adaptations Reading

MS-LS1-6:

  • Photosynthesis Lesson
  • Photosynthesis Station Activity
  • Photosynthesis Comic Book Assignment
  • Photosynthesis Infographic Assignment
  • Photosynthesis Projects PBL
  • Photosynthesis Reading
  • Why Leaves Change Color in the Fall - Reading
  • Crash Course Carbon Biological Molecules Video Worksheet
  • Carbon Cycle Diagram Activity

MS-LS1-7:

  • Cellular Respiration Lesson
  • Carbon Cycle Diagram Activity
  • Cellular Respiration - Station Activity
  • Crash Course - Do Cells Breathe Video Worksheet
  • Photosynthesis and Cellular Respiration - Crossword Puzzle Activity
  • Photosynthesis and Cellular Respiration BINGO
  • Photosynthesis and Cellular Respiration Lab Station Activity
  • Photosynthesis and Cellular Respiration Word Search and Scramble Activity

MS-LS1-8:

  • How Do We Sense the World Around Us?
  • Sensory Receptors and Memories Station Activity


MS-LS2: Interactions, Energy, & Dynamics

Ecosystem interactions, energy flow/food webs, cycling of matter, population dynamics, biodiversity, and human impacts (incl. climate change). Includes lessons, stations, digital INB, scavenger hunts, case studies, and video worksheets.

MS-LS2-1:

  • Food Chains and Food Webs - Energy Flow in Ecosystems Lesson and Worksheet
  • Populations and Resource Availability Station Activity
  • Interactions Within Ecosystems Lab Station Activity
  • Biotic and Abiotic Population Influences Lesson
  • Predator Prey Relationships Reading
  • Crash Course Ecology Video Worksheet Population Ecology
  • Biodiversity Culminating Project Bundle
  • Biodiversity and Invasive Species Lesson

MS-LS2-2:

  • Biodiversity and Interrelationships Species Interactions and Relationships Lesson
  • Biotic and Abiotic Population Influences Lesson
  • Predator Prey Relationships Reading
  • Ecosystems Interactions - Abiotic and Biotic - Station Activity
  • Crash Course Video Worksheet - Predators

MS-LS2-3:

  • Cycling of Matter Lesson
  • Food Chains and Food Webs - Energy Flow in Ecosystems Lesson
  • Matter and Energy Cycling in Ecosystems - Station Activity
  • Cycling of Matter in Ecosystems - Water and Carbon Cycles – Scavenger Hunt
  • Cycling of Matter Digital INB
  • The Carbon and Water Cycle - Lab Station Activity
  • Water and Carbon Cycle Diagram Activity

MS-LS2-4:

  • Biotic and Abiotic Population Influences Lesson
  • Predator Prey Relationships Reading
  • Biodiversity and Invasive Species Lesson
  • Environmental Changes in Ecosystems - Station Activity
  • Climate Change Lesson
  • Crash Course Video Worksheet The Effects of Climate Change
  • Crash Course Video Worksheet What is Climate Change
  • Biodiversity and Climate Change Lesson
  • Case Study - Koalas and Climate Change
  • Fracking and Its Dangers Reading
  • Invasive Species Reading
  • Invasive Species Digital Scavenger Hunt
  • Invasive Species Digital Interactive Notebook Pages

MS-LS2-5:

  • Biodiversity and Invasive Species Lesson
  • Biodiversity Culminating Project Bundle
  • The Devastating Impact of Industrial Pollution on Local Water Source
  • The Effects of Pollution Reading
  • Water Filtration Engineering Challenge
  • Weathering, Erosion, and Deposition Lesson
  • Biodiversity and Ecosystem Services - Station Activity

MS-LS3: Heredity—Inheritance & Variation of Traits

Genes, mutations, and asexual vs. sexual reproduction with hands-on practice (Punnett squares, modeling). Includes lessons, stations, readings, “Create-a-Creature” activity, and video worksheets.

MS-LS3-1:

  • DNA Genes and Mutations Lesson
  • Mutations and Inheritance of Traits - Station Activity
  • DNA Paternity Tests Reading
  • Gregor Mendel - Reading
  • Crash Course Video Worksheet How Genes Express Themselves

MS-LS3-2:

  • How Traits Are Passed On — Asexual vs Sexual Reproduction Lesson
  • Punnett Square Practice Traits in Action - Activity
  • Create-a-Creature Reproduction Models – Activity
  • Bill Nye Vide Worksheet - GENES
  • Asexual and Sexual Reproduction Station Activity
  • Crash Course Biology 47 Sexual and Asexual Reproduction
  • Plant Reproduction Lesson
  • Plant Reproduction - Scavenger Hunt


MS-LS4: Biological Evolution—Unity & Diversity

Fossils and geologic time, common ancestry (comparative anatomy/embryology), natural selection & adaptations, and impacts of artificial selection/genetic technologies. Includes lessons, stations, readings, research tasks (e.g., GMO), and video worksheets.

MS-LS4-1:

  • Fossils and Geologic Time Lesson
  • Fossils Reading
  • Evidence of Evolution in Fossils - Station Activity
  • Fossils and Geologic Time Lab Station Activity

MS-LS4-2:

  • Evolution Lesson
  • Fossils Reading
  • Common Ancestry - Station Activity
  • Evolution - Scavenger Hunt
  • Crash Course Video Worksheet - The Timeline of Life

MS-LS4-3:

  • Comparing Embryos Evidence of Common Ancestry and Evolution Lesson
  • Comparative Embryology - Station Activity
  • Crash Course Video Worksheet Human Evolution and Chimps

MS-LS4-4:

  • Physical & Behavioral Adaptations Lesson
  • Natural Selection Lesson
  • Natural Selection and Adaptation - Station Activity
  • Physical Adaptations Reading
  • Animal Adaptations Reading
  • Crash Course Video Worksheet Population Genetics

MS-LS4-5:

  • Genetic Technologies and Gene Therapy Lesson
  • Reproductive Technologies Lesson
  • Reproductive Technologies - Scavenger Hunt
  • Artificial Selection - Station Activity
  • GMO Research Activity
  • Genetically Modified Organisms Reading
  • Genetics and Gene Therapy Reading

MS-LS4-6:

  • Physical & Behavioral Adaptations Lesson
  • Natural Selection and Population Modeling - Station Activity
  • Physical Adaptations Reading
  • Natural Selection Lesson
  • Animal Adaptations Reading
  • Crash Course Video Worksheet - Life’s Way of Stayin Alive

Resource Types You’ll Use All Year

  • Complete lesson presentations (teacher & student versions)
  • Lab stations/activities and engineering-style investigations
  • Readings, scavenger hunts, vocabulary games
  • Digital Interactive Notebook pages
  • Video worksheets These formats are explicitly included across the four bundles and are organized by standard for quick planning.

Perfect For

  • Grades 6–8 Life Science pacing for a semester or full-year sequence
  • Core instruction, stations, reinforcement, intervention, and enrichment

Standards Covered

  • MS-LS1, MS-LS2, MS-LS3, MS-LS4 (NGSS Middle School Life Science).

Save time, boost engagement, and confidently meet every MS-LS expectation with one comprehensive bundle.

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Meet the Seller

Middle and High School Science Engaging Resources

I have been selling resources to middle and high school teachers for the last 15 years. During that time I've also been in the classroom so I know what works and what will help your students the most.

Canada

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