High School Handouts

The Sleep Deprivation Health Mystery – Detective SUB PLAN | Circadian Rhythm

Created by
TWFScience

Turn your students into science detectives with this NO PREP, engaging, real-world investigation focused on sleep deprivation and whole-body health disruption. In this case file activity, students analyze sleep logs, examine laboratory test results, track hormone pathways, rank possible causes, and

7th - 11th Anatomy, Biology, General Science

NGSS MS-LS1-1, MS-LS1-2, MS-LS1-3+4

Also included in: Science Detective Mystery Bundle | Chemistry, Human Body, Environmental Science

The Autoimmune Disorder Mystery – Detective SUB PLAN | Immunity, Body Systems

Created by
TWFScience

Turn your students into science detectives with this NO PREP, engaging, real-world investigation focused on immune system malfunction and autoimmune disorders. In this case file activity, students analyze laboratory data, examine inflammatory markers, evaluate antibody test results, track immune pat

7th - 11th Anatomy, Biology, General Science

NGSS MS-LS1-1, MS-LS1-2, MS-LS1-3+4

Also included in: Science Detective Mystery Bundle | Chemistry, Human Body, Environmental Science

The Blood Types Mystery – Detective SUB PLAN | ABO, Rh factor, Body Systems

Created by
TWFScience

Create a classroom full of science detectives with this NO PREP, engaging, real-world investigation focused on blood types, transfusion compatibility, and immune system response. In this case file activity, students analyze laboratory results, examine transfusion reactions, track antibody pathways,

7th - 11th Anatomy, Biology, General Science

NGSS MS-LS1-1, MS-LS1-2, MS-LS1-3+4

Also included in: Science Detective Mystery Bundle | Chemistry, Human Body, Environmental Science

The Dehydration & Electrolyte Imbalance Mystery – Detective SUB PLAN

Created by
TWFScience

Turn your students into science detectives with this NO PREP, engaging, real-world investigation focused on hydration, electrolyte balance, and whole-body system stability. In this case file activity, students analyze medical data, examine laboratory test results, track fluid and electrolyte pathway

7th - 11th Anatomy, Biology, General Science

NGSS MS-LS1-1, MS-LS1-2, MS-LS1-3+4

Also included in: Science Detective Mystery Bundle | Chemistry, Human Body, Environmental Science

The Immune System Breakdown Mystery – Detective SUB PLAN | Body Systems

Created by
TWFScience

Turn your students into science detectives with this NO PREP, engaging, real-world investigation focused on immune system breakdown and whole-body health disruption. In this case file activity, students analyze laboratory reports, examine white blood cell counts, track stress hormone patterns, evalu

7th - 11th Anatomy, Biology, General Science

NGSS MS-LS1-1, MS-LS1-2, MS-LS1-3+4

Also included in: Science Detective Mystery Bundle | Chemistry, Human Body, Environmental Science

The Screen Time Addiction & Mental Health Mystery – Detective SUB PLAN |

Created by
TWFScience

Turn your students into science detectives with this NO PREP, engaging, real-world investigation focused on screen time addiction and mental health disruption. In this case file activity, students analyze daily screen use data, examine dopamine reward responses, track sleep hormone disruption, evalu

7th - 11th Anatomy, Biology, General Science

NGSS MS-LS1-1, MS-LS1-2, MS-LS1-3+4

Also included in: Science Detective Mystery Bundle | Chemistry, Human Body, Environmental Science

Space Science Emergency Sub Plans | 2 Days | Middle School | No Prep Worksheets

Created by
TWFScience

2-Day, Emergency Space Science Introduction Sub Plans – No Prep 6th, 7th, 8th Grade Astronomy Activities and Worksheets.Need to be away from your classroom but still want your students to continue learning meaningful science content? This print-and-go AND fully digital 2-day Emergency Sub Plan allow

5th - 9th Astronomy, Earth Sciences, General Science

NGSS MS-ESS1-2, MS-ESS1-3, MS-ETS1-1

Our Solar System Emergency Sub Plans | 2 Days | Middle School | No Prep Space

Created by
TWFScience

2-Day, Emergency Solar System Sub Plans – No Prep 6th, 7th, 8th Grade Astronomy Activities and Worksheets.Need to be away from your classroom but still want your students to continue learning meaningful science content?This print-and-go AND fully digital 2-day Emergency Sub Plan allows your students

5th - 9th Astronomy, Earth Sciences, General Science

NGSS MS-ESS1-2, MS-ESS1-3, MS-ETS1-1

Stars Emergency Sub Plans | 2 Days | Middle School | The Sun No Prep Activities

Created by
TWFScience

2-Day, Emergency Stars Sub Plans – No Prep 6th, 7th, 8th Grade Astronomy Activities and Worksheets.Need to be away from your classroom but still want your students to continue learning meaningful science content?This print-and-go AND fully digital 2-day Emergency Sub Plan allows your students to con

5th - 9th Astronomy, Earth Sciences, General Science

The Seasons Emergency Sub Plans | 2 Days | Middle School | No Prep Activities

Created by
TWFScience

2-Day, Emergency Seasons and Earth's Tilt Sub Plans – No Prep 6th, 7th, 8th Grade Earth Science and Astronomy Activities and Worksheets.Need to be away from your classroom but still want your students to continue learning meaningful science content?This print-and-go AND fully digital 2-day Emergency

5th - 9th Astronomy, Earth Sciences, General Science

NGSS MS-ESS1-1

Four Seasons Data Graphing Lab Bundle | 6th, 7th, 8th Grade | Sun Angle Daylight

Created by
TWFScience

These three seasonal data and graphing activities will help your students understand seasonal changes while building graphing and data analysis skills. This bundle gives teachers an easy, NO PREP way to have students work with real-world environmental data to explore how seasons affect Earth’s syste

6th - 9th Graphing, Earth Sciences, Environment

NGSS MS-LS2-1, MS-ESS1-1, MS-ESS1-2+1

Also included in: Earth, Sun, & Moon Patterns - 5E Lesson Bundle | Seasons, Moon Phases, Eclipses

Climate Change & Long-Term Trends Graphing Labs | 6th, 7th, 8th Grade Science

Created by
TWFScience

These three climate change and long-term weather data graphing activities that will help your students understand climate change while building graphing and data analysis skills. This bundle gives teachers an easy, NO PREP way to have students work with real-world environmental data to explore how E

6th - 9th Graphing, Earth Sciences, Environment

NGSS MS-ESS2-5, MS-ESS2-6, MS-ESS3-3+1

Also included in: Middle School Science Graphing & Data Analysis Bundle | Real-World Data 6, 7, 8

The Acid Rain Mystery – Chemistry Detective Activity | Precipitation, pH scale

Created by
TWFScience

Turn your students into science detectives with this NO PREP, engaging, real-world investigation focused on air pollution and chemical reactions in the atmosphere. In this case file activity, students analyze rainwater pH data, examine surface damage on stone buildings, evaluate plant health pattern

6th - 10th Chemistry, General Science, Physical Science

NGSS MS-PS1-1, MS-PS1-2, MS-PS1-3+3

Also included in: Science Detective Mystery Bundle | Chemistry, Human Body, Environmental Science

Energy and Resource Use Investigation Graphing Labs | 6th, 7th 8th Grade Science

Created by
TWFScience

These three energy and resource use data graphing activities will help your students understand how energy production, carbon emissions, and resource extraction impact the environment while building strong graphing and data analysis skills. This bundle gives teachers an easy, NO PREP way to have stu

6th - 9th Graphing, Earth Sciences, Environment

NGSS MS-ESS3-1, MS-ESS3-2, MS-ESS3-3+2

Also included in: Middle School Science Graphing & Data Analysis Bundle | Real-World Data 6, 7, 8

Renewable Energy Unit Bundle | Solar, Wind, Hydro, Tidal, Biomass, Fusion

Created by
TWFScience

This NO-PREP, comprehensive Renewable Energy Bundle guides students through the science of renewable energy production by exploring how energy is generated from wind, solar, hydroelectric, biomass, tidal, and fusion sources—and how renewable energy can be stored and used to power our world—through e

7th - 10th Earth Sciences, Environment, Physical Science

NGSS MS-LS2-4, MS-ESS3-1, MS-ESS3-3+2

The Household Cleaning Products Reaction Mystery – Chemistry Detective Activity

Created by
TWFScience

Turn your students into science detectives with this NO PREP, engaging, real-world investigation focused on how household cleaning products work at the chemistry level. In this case file activity, students analyze cleaning test results, compare grease and stain removal data, evaluate disinfectant cl

6th - 10th Chemistry, General Science, Physical Science

NGSS MS-PS1-1, MS-PS1-2, MS-PS1-3+3

Also included in: Science Detective Mystery Bundle | Chemistry, Human Body, Environmental Science

The Conductivity Case Mystery – Chemistry Detective Activity | Current, Circuit

Created by
TWFScience

Turn your students into science detectives with this NO PREP, engaging, real-world investigation focused on why some liquids conduct electricity while others do not. In this case file activity, students analyze conductivity test results, compare salt water, sugar water, vinegar, baking soda, tap wat

6th - 10th Chemistry, General Science, Physical Science

NGSS MS-PS1-1, MS-PS1-2, MS-PS1-3+3

Also included in: Science Detective Mystery Bundle | Chemistry, Human Body, Environmental Science

The Energy Release Mystery – Chemistry Detective Activity | Exothermic, Reaction

Created by
TWFScience

Turn your students into science detectives with this NO PREP, engaging, real-world investigation focused on how and why some chemical reactions release energy rapidly. In this case file activity, students analyze temperature changes, observe gas production, evaluate reaction speed data, examine syst

6th - 10th Chemistry, General Science, Physical Science

NGSS MS-PS1-1, MS-PS1-2, MS-PS1-3+3

Also included in: Science Detective Mystery Bundle | Chemistry, Human Body, Environmental Science

The Phase Change Puzzle Mystery | Detective Activity | States of Matter

Created by
TWFScience

Turn your students into science detectives with this NO PREP, engaging, real-world investigation focused on why matter changes state without changing its identity. In this physical change vs chemical change case file activity, students analyze melting and freezing, evaporation, and condensation obse

6th - 10th Chemistry, General Science, Physical Science

NGSS MS-PS1-1, MS-PS1-2, MS-PS1-3+3

Also included in: Science Detective Mystery Bundle | Chemistry, Human Body, Environmental Science

The Missing Mass Mystery - Chemistry Detective Activity | Conservation of Mass

Created by
TWFScience

Turn your students into science detectives with this NO PREP, engaging, real-world investigation focused on the Law of Conservation of Mass. In this case file activity, students analyze mass measurements, examine gas formation data, compare open and closed systems, evaluate dissolving observations,

6th - 10th Chemistry, General Science, Physical Science

NGSS MS-PS1-1, MS-PS1-2, MS-PS1-3+3

Also included in: Science Detective Mystery Bundle | Chemistry, Human Body, Environmental Science

The Ozone Layer Mystery - Chemistry Detective Activity | Ultraviolet Radiation

Created by
TWFScience

Turn your students into science detectives with this NO PREP, engaging, real-world investigation focused on what protects Earth from harmful radiation. In this case file activity, students analyze UV radiation data, examine ozone concentration trends, evaluate atmospheric chemistry evidence, track h

6th - 10th Chemistry, General Science, Physical Science

NGSS MS-PS1-1, MS-PS1-2, MS-PS1-3+3

Also included in: Science Detective Mystery Bundle | Chemistry, Human Body, Environmental Science

The Plastic Breakdown Mystery - Chemistry Detective Activity | Microplastics

Created by
TWFScience

Turn your students into science detectives with this NO PREP, engaging, real-world investigation focused on why plastic lasts so long in the environment. In this case file activity, students analyze environmental observations, examine sunlight exposure data, compare decomposition patterns, evaluate

6th - 10th Chemistry, General Science, Physical Science

NGSS MS-PS1-1, MS-PS1-2, MS-PS1-3+3

Also included in: Science Detective Mystery Bundle | Chemistry, Human Body, Environmental Science

The Solubility Surprise Mystery - Chemistry Detective Activity | Solute, Solvent

Created by
TWFScience

Turn your students into science detectives with this NO PREP, engaging, real-world investigation focused on why some substances dissolve while others do not. In this case file activity, students analyze dissolving observations, examine temperature effects, compare different substances in water, eval

6th - 10th Chemistry, General Science, Physical Science

NGSS MS-PS1-1, MS-PS1-2, MS-PS1-3+3

Also included in: Science Detective Mystery Bundle | Chemistry, Human Body, Environmental Science

The Spoiled Food Mystery - Chemistry Detective Activity | Microorganisms Microbe

Created by
TWFScience

Turn your students into science detectives with this NO PREP, engaging, real-world investigation focused on why food changes over time. In this case file activity, students analyze food spoilage observations, examine environmental conditions, compare storage methods, evaluate microbial activity evid

6th - 10th Chemistry, General Science, Physical Science

NGSS MS-PS1-1, MS-PS1-2, MS-PS1-3+3

Also included in: Science Detective Mystery Bundle | Chemistry, Human Body, Environmental Science