Science Hands-On Activities

Cell Organelles Logic Puzzles - Determine the Mystery Organelle Activities

Created by
TWFScience

Cell Organelles Activity - FOUR Logic Puzzles that let your students become cell organelle detectives Looking for a way to teach cell organelles that goes beyond worksheets and memorization?This Mystery Organelle Logic Lab challenges students to use deductive reasoning, evidence, and scientific thin

6th - 9th Biology, General Science

NGSS MS-LS1-1, MS-LS1-2, MS-LS1-3

Artificial Intelligence and Machines Learning Reading | Grade 8 & Up Activity

Created by
TWFScience

Artificial Intelligence is rapidly changing the world, and this Reading Comprehension Passage and Questions helps students understand what AI is, how it works, and why it matters. It explains how machines are able to learn from data, recognize patterns, and make decisions, as well as the difference

9th - 12th Science, General Science, Physical Science

Also included in: Science Reading Comprehension Article Mega Bundle | Grade 8 and Up

CRISPR Gene Editing: Rewriting the Code of Life Reading | Grade 8 & Up Activity

Created by
TWFScience

CRISPR Gene Editing Reading Comprehension Passage and Questions. CRISPR gene editing is one of the most powerful scientific developments of the 21st century, and this Reading Comprehension Passage and Questions article helps students understand what CRISPR is, how it works, and why it matters. It ex

9th - 12th Science, Biology, General Science

Also included in: Genetics, Heredity, DNA, and Traits - 5E Lesson Bundle | Genotype and Phenotype

Biology Case Study - CRISPR and Sickle Cell Disease | Reading

Created by
TWFScience

Biology Case Study “CRISPR and Sickle Cell Disease”This resource provides an engaging look at how CRISPR gene editing is being used to fix mistakes in DNA through a real-world case study of sickle cell disease. Students explore how DNA acts as the instruction code for cells and how changes in struct

7th - 10th Biology, General Science

Also included in: Science Case Study Bundle - Ecology, Chemistry, Physics, Biology, and Space

Gene-Edited Pig Organs & Xenotransplantation Reading | Grade 8 & Up Activity

Created by
TWFScience

Xenotransplantation and gene-edited organ transplants Reading Comprehension Passage and Questions. Gene edited organ transplants represent one of the most groundbreaking medical advances of the 21st century, and this reading comprehension article helps students understand how and why pig organs are

9th - 12th Science, Biology, General Science

Also included in: Science Reading Comprehension Article Mega Bundle | Grade 8 and Up

Microplastics and Plastic Pollution Reading | Grade 8 & Up Activity

Created by
TWFScience

Microplastics and plastic pollution Reading Comprehension Passage and Questions. Microplastics and plastic pollution are among the most urgent environmental issues of the 21st century, and this reading comprehension article helps students understand how plastic waste is affecting ecosystems and huma

9th - 12th Science, Biology, Chemistry

Also included in: Human Impact & Sustainability - 13 Reading Comprehension Bundle | Grade 8 and Up

Electromagnet - Coil Turns vs Magnetic Strength STEM Investigation

Created by
TWFScience

Students will investigate electromagnetism by building their own classroom-made electromagnets and testing how changing the number of wire coils affects magnetic strength. Using an iron nail, insulated wire, a battery, and paper clips, students observe how electric current creates a magnetic field a

6th - 11th Basic Principles, Physical Science, Physics

NGSS MS-PS2-3, MS-PS2-5, MS-ETS1-1+2

Also included in: STEM Investigations Growing Bundle — Scientific Method, Design, Data & CER

Microplastics Mystery – Human Impact Detective on Plastic Pollution | SUB PLAN

Created by
TWFScience

Turn your students into science detectives with this engaging, real-world investigation focused on microplastics and plastic pollution. In this case file activity, students analyze evidence, track pollution pathways, interrogate suspects, and build a scientific case to solve the mystery of how micro

6th - 9th Biology, Earth Sciences, General Science

Also included in: Science Detective Mystery Bundle | Chemistry, Human Body, Environmental Science

Supervolcanoes and Mega-Eruptions Reading | Grade 8 & Up Activity

Created by
TWFScience

Supervolcanoes and mega-eruptions are among the most powerful natural events on Earth, and this reading comprehension article and questions article helps students understand how these massive volcanic systems form and why they matter. It explains what supervolcanoes are, how they differ from regular

9th - 12th Science, Biology, Earth Sciences

Also included in: Science Reading Comprehension Article Mega Bundle | Grade 8 and Up

The Rock Cycle - Igneous, Sedimentary, Metamorphic Rocks Reading | Grade 8 & Up

Created by
TWFScience

The rock cycle is one of the most important concepts in Earth science, and this reading comprehension article helps students understand how igneous, sedimentary, and metamorphic rocks form and change over time. It explains how rocks are created by melting and cooling, broken down by weathering and e

8th - 12th Science, Biology, Earth Sciences

Also included in: Science Reading Comprehension Article Mega Bundle | Grade 8 and Up

Microplastics & Plastic Pollution Lesson | 7th, 8th, 9th Grade | Human Impact

Created by
TWFScience

This lesson on Microplastics & Plastic Pollution specifically covers what microplastics are, how they form, how they move through ecosystems and food chains, their impact on human health, and why they are difficult to remove. Additionally, your lesson includes my Microplastics Mystery Activity w

6th - 9th Chemistry, General Science, Physical Science

Plastics and their Environmental Impact Bundle - Microplastics | High School

Created by
TWFScience

This NO-PREP bundle includes lessons, readings, worksheets, and multiple case studies focused on plastics, microplastics, polymers, and plastic pollution.Students build a deep, evidence-based understanding of plastics as both a scientific innovation and an environmental challenge through a carefully

9th - 11th Chemistry, Earth Sciences, Physical Science

The Air Pollution Mystery – Science Detective | Human Impact | SUB PLAN

Created by
TWFScience

Turn your students into science detectives with this engaging, real-world investigation focused on air pollution. In this case file activity, students analyze evidence, track pollution pathways, interrogate suspects, and build a scientific case to solve the mystery of how air pollution is affecting

6th - 9th Biology, Earth Sciences, General Science

Also included in: Science Detective Mystery Bundle | Chemistry, Human Body, Environmental Science

Oobleck: Force vs Flow — Non-Newtonian Fluids STEM Investigation

Created by
TWFScience

Students will investigate non-Newtonian fluids by creating oobleck and testing how different types of force affect whether it behaves like a solid or a liquid. Using cornstarch and water, students observe how fast force causes oobleck to act solid while slow force allows it to flow like a liquid. Th

6th - 11th Chemistry, Physical Science, Physics

Also included in: STEM Investigations Growing Bundle — Scientific Method, Design, Data & CER

The Water Pollution Mystery – Human Impact Science Detective | SUB PLAN

Created by
TWFScience

Turn your students into science detectives with this engaging, real-world investigation focused on water pollution. In this case file activity, students analyze evidence, track pollution pathways, interrogate suspects, and build a scientific case to solve the mystery of how water pollution is damagi

6th - 9th Biology, Earth Sciences, General Science

Also included in: Science Detective Mystery Bundle | Chemistry, Human Body, Environmental Science

Deforestation & Habitat Destruction Mystery – Human Impact Detective | SUB PLAN

Created by
TWFScience

Turn your students into science detectives with this engaging, real-world investigation focused on deforestation and habitat destruction. In this case file activity, students analyze evidence, track environmental pathways, interrogate suspects, and build a scientific case to solve the mystery of why

6th - 9th Biology, Earth Sciences, General Science

NGSS MS-ESS3-3, MS-ESS3-4

Also included in: Science Detective Mystery Bundle | Chemistry, Human Body, Environmental Science

The Biodiversity Loss Mystery – Human Impact Detective | SUB PLAN | Environment

Created by
TWFScience

Turn your students into science detectives with this engaging, real-world investigation focused on biodiversity loss and species decline. In this case file activity, students analyze evidence, track ecological pathways, interrogate suspects, and build a scientific case to solve the mystery of why sp

6th - 9th Biology, Earth Sciences, General Science

NGSS MS-LS2-1, MS-LS2-4, MS-LS2-5+3

Also included in: Science Detective Mystery Bundle | Chemistry, Human Body, Environmental Science

The Invasive Species Mystery – Human Impact Detective | SUB PLAN | Environment

Created by
TWFScience

Turn your students into science detectives with this engaging, real-world investigation focused on invasive species and ecosystem disruption. In this case file activity, students analyze evidence, track ecological pathways, interrogate suspects, and build a scientific case to solve the mystery of ho

6th - 9th Biology, Earth Sciences, General Science

NGSS MS-LS2-1, MS-LS2-4, MS-LS2-5+3

Also included in: Science Detective Mystery Bundle | Chemistry, Human Body, Environmental Science

Climate Change and Global Warming Mystery – Human Impact Detective | SUB PLAN

Created by
TWFScience

Turn your students into science detectives with this engaging, real-world investigation focused on climate change and global warming. In this case file activity, students analyze evidence, track environmental pathways, interrogate suspects, and build a scientific case to solve the mystery of why Ear

6th - 9th Biology, Earth Sciences, General Science

NGSS MS-LS2-1, MS-LS2-4, MS-LS2-5+3

Also included in: Science Detective Mystery Bundle | Chemistry, Human Body, Environmental Science

Overfishing & Ocean Ecosystem Collapse Mystery – Detective | SUB PLAN

Created by
TWFScience

Turn your students into science detectives with this engaging, real-world investigation focused on overfishing and ocean ecosystem collapse. In this case file activity, students analyze evidence, track ecological pathways, interrogate suspects, and build a scientific case to solve the mystery of why

6th - 9th Biology, Earth Sciences, General Science

NGSS MS-LS2-1, MS-LS2-4, MS-LS2-5+3

Also included in: Science Detective Mystery Bundle | Chemistry, Human Body, Environmental Science

The Resource Depletion & Mining Mystery – Human Impact Detective | SUB PLAN

Created by
TWFScience

Turn your students into science detectives with this engaging, real-world investigation focused on resource depletion and mining damage. In this case file activity, students analyze evidence, track environmental pathways, interrogate suspects, and build a scientific case to solve the mystery of why

6th - 9th Biology, Earth Sciences, General Science

NGSS MS-LS2-1, MS-LS2-4, MS-LS2-5+3

Also included in: Science Detective Mystery Bundle | Chemistry, Human Body, Environmental Science

The Urban Sprawl Mystery – Detective SUB PLAN | Human Impact on the Environment

Created by
TWFScience

Turn your students into science detectives with this engaging, real-world investigation focused on urban sprawl and land use change. In this case file activity, students analyze evidence, track environmental pathways, interrogate suspects, and build a scientific case to solve the mystery of how citi

6th - 9th Biology, Earth Sciences, General Science

NGSS MS-LS2-1, MS-LS2-4, MS-LS2-5+3

Also included in: Science Detective Mystery Bundle | Chemistry, Human Body, Environmental Science

Environmental Science Detective Mystery Bundle | Human Impact | SUB PLAN

Created by
TWFScience

Build a high-engagement, low-prep environmental science program that grows with you. This Bundle collects my complete Science Detective Mystery Case Files—each one built around real-world environmental problems, evidence analysis, pathway tracking, suspect ranking, and Claim–Evidence–Reasoning (CER)

6th - 9th Biology, Earth Sciences, General Science

NGSS MS-LS2-1, MS-LS2-2, MS-LS2-3+6

The Landfill & Waste Crisis Mystery – Detective Case File | Human Impact

Created by
TWFScience

Turn your students into science detectives with this engaging, real-world investigation focused on the waste crisis and landfill pollution. In this case file activity, students analyze evidence, track environmental pathways, interrogate suspects, and build a scientific case to solve the mystery of h

6th - 9th Biology, Earth Sciences, General Science

NGSS MS-LS2-1, MS-LS2-4, MS-LS2-5+3

Also included in: Science Detective Mystery Bundle | Chemistry, Human Body, Environmental Science