11th Grade Handouts

The Oxygen Delivery Crisis Mystery – Detective SUB PLAN | Human Body System

Created by
TWFScience

The Oxygen Delivery Crisis Mystery – Turn your students into science detectives with this engaging, real-world investigation focused on oxygen delivery in the human body and what happens when oxygen fails to reach cells efficiently—even when breathing appears normal. In this case file activity, stud

7th - 11th Anatomy, Biology, General Science

NGSS MS-LS1-1, MS-LS1-2, MS-LS1-3+4

Also included in: Science Detective Mystery Bundle | Chemistry, Human Body, Environmental Science

The Substance Abuse Impact on Body Systems Mystery – Detective SUB PLAN Activity

Created by
TWFScience

The Substance Abuse & Impact on Body Systems Mystery – Turn your students into science detectives with this engaging, real-world investigation focused on substance use and how vaping, smoking, and alcohol affect multiple body systems. In this case file activity, students analyze medical and labo

7th - 11th Anatomy, Biology, General Science

NGSS MS-LS1-1, MS-LS1-2, MS-LS1-3+4

Also included in: Science Detective Mystery Bundle | Chemistry, Human Body, Environmental Science

Earth Day Countdown | 22 Environmental Science Starter Slides | Earth Day Warmup

Created by
TWFScience

Earth Day Countdown – Class Starter Discussion Slides & Teacher Guide. 22 Days of Discussion and Collaboration. Fully editable.Looking for an engaging way to spark meaningful conversations about environmental issues leading up to Earth Day or just how humans impact the environment? This Earth Da

6th - 11th Biology, Earth Sciences, Marine Science

NGSS MS-LS2-1, MS-LS2-4, MS-ESS3-1+9

Earth Day Countdown | Environmental Class Starter 3-DAY SAMPLE

Created by
TWFScience

Earth Day Countdown SAMPLE – Class Starter Discussion Slides & Teacher Guide. 3 Days of Discussion and Collaboration. The full version - Earth Day Countdown | 22 Environmental Class Starter Slides for Discussion and Collaboration can be found by clicking here.The full version contains 22, fully

6th - 11th Biology, Earth Sciences, Marine Science

NGSS MS-LS2-1, MS-LS2-4, MS-ESS3-1+9

The Blood Sugar Balance Mystery – Detective SUB PLAN | Insulin, Cells, Pancreas

Created by
TWFScience

Turn your students into science detectives with this NO PREP, engaging, real-world investigation focused on health and blood glucose balance. In this case file activity, students analyze medical data, examine laboratory test results, track hormone pathways, interrogate suspects, and build a scientif

7th - 11th Anatomy, Biology, General Science

NGSS MS-LS1-1, MS-LS1-2, MS-LS1-3+4

Also included in: Science Detective Mystery Bundle | Chemistry, Human Body, Environmental Science

The Foodborne Illness Outbreak Mystery – Detective SUB PLAN | Salmonella

Created by
TWFScience

Turn your students into science detectives with this NO PREP, engaging, real-world investigation focused on foodborne illness and digestive system infection. In this case file activity, students analyze medical data, examine laboratory test results, track pathogen pathways, rank possible causes, and

7th - 11th Anatomy, Biology, General Science

NGSS MS-LS1-1, MS-LS1-2, MS-LS1-3+4

Also included in: Science Detective Mystery Bundle | Chemistry, Human Body, Environmental Science

The Musculoskeletal System Injury Mystery – Detective SUB PLAN | Bones, Tendons

Created by
TWFScience

Turn your students into science detectives with this NO PREP, engaging, real-world investigation focused on musculoskeletal system injuries and movement breakdown. In this case file activity, students analyze strength test data, examine range-of-motion measurements, investigate posture assessments,

7th - 11th Anatomy, Biology, General Science

NGSS MS-LS1-1, MS-LS1-2, MS-LS1-3+4

Also included in: Science Detective Mystery Bundle | Chemistry, Human Body, Environmental Science

The Nutrition & Diet Health Mystery – Detective SUB PLAN | Vitamins, Minerals

Created by
TWFScience

Turn your students into science detectives with this NO PREP, engaging, real-world investigation focused on nutrition, diet, and whole-body health balance. In this case file activity, students analyze medical data, examine laboratory test results, track nutrient pathways, rank possible causes, and b

7th - 11th Anatomy, Biology, General Science

NGSS MS-LS1-1, MS-LS1-2, MS-LS1-3+4

Also included in: Science Detective Mystery Bundle | Chemistry, Human Body, Environmental Science

The Sleep Deprivation Health Mystery – Detective SUB PLAN | Circadian Rhythm

Created by
TWFScience

Turn your students into science detectives with this NO PREP, engaging, real-world investigation focused on sleep deprivation and whole-body health disruption. In this case file activity, students analyze sleep logs, examine laboratory test results, track hormone pathways, rank possible causes, and

7th - 11th Anatomy, Biology, General Science

NGSS MS-LS1-1, MS-LS1-2, MS-LS1-3+4

Also included in: Science Detective Mystery Bundle | Chemistry, Human Body, Environmental Science

The Autoimmune Disorder Mystery – Detective SUB PLAN | Immunity, Body Systems

Created by
TWFScience

Turn your students into science detectives with this NO PREP, engaging, real-world investigation focused on immune system malfunction and autoimmune disorders. In this case file activity, students analyze laboratory data, examine inflammatory markers, evaluate antibody test results, track immune pat

7th - 11th Anatomy, Biology, General Science

NGSS MS-LS1-1, MS-LS1-2, MS-LS1-3+4

Also included in: Science Detective Mystery Bundle | Chemistry, Human Body, Environmental Science

The Blood Types Mystery – Detective SUB PLAN | ABO, Rh factor, Body Systems

Created by
TWFScience

Create a classroom full of science detectives with this NO PREP, engaging, real-world investigation focused on blood types, transfusion compatibility, and immune system response. In this case file activity, students analyze laboratory results, examine transfusion reactions, track antibody pathways,

7th - 11th Anatomy, Biology, General Science

NGSS MS-LS1-1, MS-LS1-2, MS-LS1-3+4

Also included in: Science Detective Mystery Bundle | Chemistry, Human Body, Environmental Science

The Dehydration & Electrolyte Imbalance Mystery – Detective SUB PLAN

Created by
TWFScience

Turn your students into science detectives with this NO PREP, engaging, real-world investigation focused on hydration, electrolyte balance, and whole-body system stability. In this case file activity, students analyze medical data, examine laboratory test results, track fluid and electrolyte pathway

7th - 11th Anatomy, Biology, General Science

NGSS MS-LS1-1, MS-LS1-2, MS-LS1-3+4

Also included in: Science Detective Mystery Bundle | Chemistry, Human Body, Environmental Science

The Immune System Breakdown Mystery – Detective SUB PLAN | Body Systems

Created by
TWFScience

Turn your students into science detectives with this NO PREP, engaging, real-world investigation focused on immune system breakdown and whole-body health disruption. In this case file activity, students analyze laboratory reports, examine white blood cell counts, track stress hormone patterns, evalu

7th - 11th Anatomy, Biology, General Science

NGSS MS-LS1-1, MS-LS1-2, MS-LS1-3+4

Also included in: Science Detective Mystery Bundle | Chemistry, Human Body, Environmental Science

The Screen Time Addiction & Mental Health Mystery – Detective SUB PLAN |

Created by
TWFScience

Turn your students into science detectives with this NO PREP, engaging, real-world investigation focused on screen time addiction and mental health disruption. In this case file activity, students analyze daily screen use data, examine dopamine reward responses, track sleep hormone disruption, evalu

7th - 11th Anatomy, Biology, General Science

NGSS MS-LS1-1, MS-LS1-2, MS-LS1-3+4

Also included in: Science Detective Mystery Bundle | Chemistry, Human Body, Environmental Science

Acids - Binary and Oxyacids Cipher Puzzle - Chemistry Naming Activity

Created by
TWFScience

Engage your students with this NO PREP, interactive chemistry cipher activity focused on binary acids, oxyacids, chemical formulas, and acid naming.In this structured challenge, students solve clues by either naming acids from formulas or writing formulas from acid names. After each answer, they ext

9th - 11th Chemistry, General Science, Physical Science

Also included in: Chemistry Concepts Cipher Puzzle Bundle | Periodic Table, Nomenclature, Stoich

Periodic Table Trends Cipher Puzzle - Chemistry Activity | Atomic Radius

Created by
TWFScience

Engage your students with this NO PREP, interactive chemistry cipher activity focused on periodic table trends, atomic radius, electronegativity, and ionization energy.In this structured challenge, students solve clues by identifying elements based on their position on the periodic table and their t

9th - 11th Chemistry, General Science, Physical Science

Also included in: Chemistry Concepts Cipher Puzzle Bundle | Periodic Table, Nomenclature, Stoich

Ionic and Molecular Compounds Cipher Puzzle - Science Activity | Nomenclature

Created by
TWFScience

Engage your students with this NO PREP, interactive chemistry cipher activity focused on ionic and molecular compounds, chemical formulas, and compound naming.In this structured challenge, students solve clues by either naming compounds from formulas or writing formulas from compound names. After ea

9th - 12th Chemistry, General Science, Physical Science

Also included in: Chemical Bonding, Compounds, and Intermolecular Forces 5E Unit Bundle

Ionic and Polyatomic Compounds Cipher Puzzle | Naming and Formula Writing

Created by
TWFScience

Engage your students with this NO PREP, interactive chemistry cipher activity focused on ionic compounds, polyatomic ions, multivalent metals, and chemical formulas.In this structured challenge, students solve clues by either naming compounds from formulas or writing formulas from compound names. Af

9th - 12th Chemistry, General Science, Physical Science

Also included in: SNC2D Ontario Grade 10 Science Chemistry - Chemical Reactions Full Course Unit

Acid–Base Calculation Cipher Puzzle - Chemisty Activity | Solving pH/pOH

Created by
TWFScience

Engage your students with this NO PREP, interactive chemistry cipher activity focused on pH, pOH, [H⁺], [OH⁻], and acid-base calculations.In this structured challenge, students solve clues by completing acid-base calculations involving pH, pOH, hydrogen ion concentration, and hydroxide ion concentra

10th - 12th Chemistry, General Science, Physical Science

Also included in: Chemistry Concepts Cipher Puzzle Bundle | Periodic Table, Nomenclature, Stoich

Ionic, Polyatomic, Molecular Compounds Cipher Puzzle - Naming & Formula Writing

Created by
TWFScience

Engage your students with this NO PREP, interactive chemistry cipher activity focused on ionic, polyatomic, and molecular compounds, chemical formulas, and compound naming.In this structured challenge, students solve clues by either naming compounds from formulas or writing formulas from compound na

10th - 12th Chemistry, General Science, Physical Science

Also included in: SNC2D Ontario Grade 10 Science Chemistry - Chemical Reactions Full Course Unit

Types of Reactions and Balancing Cipher Puzzle - Chemistry Science Activity

Created by
TWFScience

Engage your students with this NO PREP, interactive chemistry cipher activity focused on balancing chemical equations and identifying reaction types.In this structured challenge, students first balance each chemical equation, then identify the type of reaction as synthesis, decomposition, single rep

10th - 12th Chemistry, General Science, Physical Science

Also included in: Chemistry Concepts Cipher Puzzle Bundle | Periodic Table, Nomenclature, Stoich

Molecular Compounds Cipher Puzzle - Nomenclature | Naming and Formula Writing

Created by
TWFScience

Engage your students with this NO PREP, interactive chemistry cipher activity focused on molecular compounds, chemical formulas, prefixes, and compound naming.In this structured challenge, students solve clues by either naming molecular compounds from formulas or writing formulas from compound names

10th - 12th Chemistry, General Science, Physical Science

Also included in: Chemical Bonding, Compounds, and Intermolecular Forces 5E Unit Bundle

Artemis III Mission Patch Design Project | NASA Space Activity | All Grades

Created by
TWFScience

In this project, your students will research the Artemis III mission, decide which mission ideas matter most, and turn those ideas into an original mission patch. Students explore mission goals, spacecraft and systems, future Moon exploration, and the symbolism used in real mission patches. They mus

5th - 12th Astronomy, Engineering, Physical Science

NGSS MS-PS2-2, MS-PS2-4, MS-ETS1-1+3

Also included in: Artemis Missions, Moon Bases, and Future Space Colonization Unit Bundle

Living in Deep Space - Astronaut Survival Systems Project | NASA, Artemis II

Created by
TWFScience

In this project, your students will work in groups to figure out how astronauts survive during a space mission like the Artemis missions. Each student becomes the team expert for one major survival system—oxygen, water, food, temperature control, or waste management—and then teaches the class throug

7th - 11th Astronomy, Engineering, Physical Science

NGSS MS-ESS1-3, MS-ETS1-1, MS-ETS1-2+2

Also included in: Artemis Missions, Moon Bases, and Future Space Colonization Unit Bundle