General Science Activities

Germ Theory Reading - Germs and the Immune System, Disease | 6th, 7th, 8th Grade

Created by
TWFScience

This grade 6–8 reading comprehension article and questions introduces students to germ theory—the scientific discovery that microorganisms cause many diseases. Students explore how this idea revolutionized medicine, changed hygiene practices, and continues to shape public health today. From the work

6th - 8th Anatomy, Biology, General Science

NGSS MS-LS1-2, MS-LS1-3

Also included in: Reading Comprehension Article & Question Mega Bundle | 6th, 7th, 8th Grade

The Missing Mass Mystery - Chemistry Detective Activity | Conservation of Mass

Created by
TWFScience

Turn your students into science detectives with this NO PREP, engaging, real-world investigation focused on the Law of Conservation of Mass. In this case file activity, students analyze mass measurements, examine gas formation data, compare open and closed systems, evaluate dissolving observations,

6th - 10th Chemistry, General Science, Physical Science

NGSS MS-PS1-1, MS-PS1-2, MS-PS1-3+3

Also included in: Science Detective Mystery Bundle | Chemistry, Human Body, Environmental Science

The Ozone Layer Mystery - Chemistry Detective Activity | Ultraviolet Radiation

Created by
TWFScience

Turn your students into science detectives with this NO PREP, engaging, real-world investigation focused on what protects Earth from harmful radiation. In this case file activity, students analyze UV radiation data, examine ozone concentration trends, evaluate atmospheric chemistry evidence, track h

6th - 10th Chemistry, General Science, Physical Science

NGSS MS-PS1-1, MS-PS1-2, MS-PS1-3+3

Also included in: Science Detective Mystery Bundle | Chemistry, Human Body, Environmental Science

The Plastic Breakdown Mystery - Chemistry Detective Activity | Microplastics

Created by
TWFScience

Turn your students into science detectives with this NO PREP, engaging, real-world investigation focused on why plastic lasts so long in the environment. In this case file activity, students analyze environmental observations, examine sunlight exposure data, compare decomposition patterns, evaluate

6th - 10th Chemistry, General Science, Physical Science

NGSS MS-PS1-1, MS-PS1-2, MS-PS1-3+3

Also included in: Science Detective Mystery Bundle | Chemistry, Human Body, Environmental Science

The Solubility Surprise Mystery - Chemistry Detective Activity | Solute, Solvent

Created by
TWFScience

Turn your students into science detectives with this NO PREP, engaging, real-world investigation focused on why some substances dissolve while others do not. In this case file activity, students analyze dissolving observations, examine temperature effects, compare different substances in water, eval

6th - 10th Chemistry, General Science, Physical Science

NGSS MS-PS1-1, MS-PS1-2, MS-PS1-3+3

Also included in: Science Detective Mystery Bundle | Chemistry, Human Body, Environmental Science

The Spoiled Food Mystery - Chemistry Detective Activity | Microorganisms Microbe

Created by
TWFScience

Turn your students into science detectives with this NO PREP, engaging, real-world investigation focused on why food changes over time. In this case file activity, students analyze food spoilage observations, examine environmental conditions, compare storage methods, evaluate microbial activity evid

6th - 10th Chemistry, General Science, Physical Science

NGSS MS-PS1-1, MS-PS1-2, MS-PS1-3+3

Also included in: Science Detective Mystery Bundle | Chemistry, Human Body, Environmental Science

Chemistry in Everyday Life Detective Mystery Bundle | Physical Science Activity

Created by
TWFScience

This BUNDLE is composed of high-engagement, no-prep Chemistry in Everyday Life activities that grow with you. This bundle consists of mystery activities that examine everyday chemical reactions and guide your students through evidence analysis, pathway tracking, suspect ranking, and Claim–Evidence–R

7th - 11th Chemistry, General Science, Physical Science

NGSS MS-PS1-1, MS-PS1-2, MS-PS1-4+2

Resource Depletion & Mining Reading | Ore Extraction, Tailings | 6th, 7th, 8th

Created by
TWFScience

Resource Depletion & Mining is topic that helps students explore how natural resources are used, why mining is necessary for modern life, and how resource depletion affects ecosystems, communities, and economies. This reading comprehension article and questions introduces the science and environ

6th - 8th Earth Sciences, Environment, General Science

NGSS MS-ESS3-1, MS-ESS3-3

Also included in: Human Impact & Sustainability - 13 Reading Article Bundle - 6th 7th 8th Grade

Disease Spread & Public Health Data Graphing Labs | 6th, 7th, 8th Grade Science

Created by
TWFScience

These three disease spread and public health data graphing activities will help your students understand how infectious diseases spread and how prevention strategies impact public health while building strong graphing and data analysis skills. This bundle gives teachers an easy, NO PREP way to have

6th - 9th Graphing, Biology, General Science

NGSS MS-ESS2-1, MS-ESS2-2, MS-ESS2-3

Also included in: Middle School Science Graphing & Data Analysis Bundle | Real-World Data 6, 7, 8

Spring Environmental Data Graphing Lab Bundle | 6th, 7th, 8th Grade | Seasons

Created by
TWFScience

These three spring environmental change data graphing activities will help your students understand how seasonal climate conditions influence ecosystems while building strong graphing and data analysis skills. This bundle gives teachers an easy, NO PREP way to have students work with real-world envi

6th - 9th Graphing, Biology, General Science

NGSS MS-ESS2-1, MS-ESS2-4, MS-ESS2-6

Also included in: Middle School Science Graphing & Data Analysis Bundle | Real-World Data 6, 7, 8

Energy Transfer and Heat Investigation Graphing Lab Bundle | 6th, 7th, 8th Grade

Created by
TWFScience

These three energy transfer and heat graphing investigations help students understand how thermal energy moves through matter while building strong graphing and data analysis skills. This bundle gives teachers an easy, NO PREP way to have students work with real-world style datasets to explore Heati

6th - 9th Graphing, Biology, General Science

NGSS MS-PS3-3, MS-PS3-4

Also included in: Middle School Science Graphing & Data Analysis Bundle | Real-World Data 6, 7, 8

Middle School Science Graphing & Data Analysis Bundle | Real-World Data 6, 7, 8

Created by
TWFScience

This growing bundle of science data graphing investigations helps students explore major middle school science concepts while building strong graphing and data analysis skills. Each investigation uses real-world or real-world style datasets so students can analyze patterns, identify trends, and expl

6th - 9th Biology, Earth Sciences, General Science

NGSS MS-PS1-2, MS-PS2-1, MS-PS2-2+22

The Air Quality Alarm Mystery - Chemistry Detective Activity | Pollution, Smog

Created by
TWFScience

Turn your students into science detectives with this NO PREP, engaging, real-world investigation focused on air pollution and chemical contaminants in the atmosphere. In this case file activity, students analyze air quality data, examine pollutant sources, interpret particle measurements, evaluate c

6th - 10th Chemistry, General Science, Physical Science

NGSS MS-PS1-1, MS-PS1-2, MS-PS1-3+3

Also included in: Science Detective Mystery Bundle | Chemistry, Human Body, Environmental Science

The Density Disaster Mystery - Chemistry Detective Activity | Buoyancy, Mass

Created by
TWFScience

Turn your students into science detectives with this NO PREP, engaging, real-world investigation focused on density and buoyancy. In this case file activity, students analyze mass and volume data, examine floating and sinking observations, compare different materials, evaluate liquid density changes

6th - 10th Chemistry, General Science, Physical Science

NGSS MS-PS1-1, MS-PS1-2, MS-PS1-3+3

Also included in: Science Detective Mystery Bundle | Chemistry, Human Body, Environmental Science

The Magnetic Mix-Up Mystery - Chemistry Detective Activity | Magnetism

Created by
TWFScience

Turn your students into science detectives with this NO PREP, engaging, real-world investigation focused on magnetism and material properties. In this case file activity, students analyze magnetic test results, examine material composition, compare different metals and nonmetals, evaluate patterns i

6th - 10th Chemistry, General Science, Physical Science

NGSS MS-PS1-1, MS-PS1-2, MS-PS1-3+3

Also included in: Science Detective Mystery Bundle | Chemistry, Human Body, Environmental Science

The Rising Dough Mystery - Chemistry Detective Activity | Fermentation, Baking

Created by
TWFScience

Turn your students into science detectives with this NO PREP, engaging, real-world investigation focused on fermentation, gas production, and baking science. In this case file activity, students analyze dough observations, examine yeast activity, interpret gas formation evidence, evaluate temperatur

6th - 10th Chemistry, General Science, Physical Science

NGSS MS-PS1-1, MS-PS1-2, MS-PS1-3+3

Also included in: Science Detective Mystery Bundle | Chemistry, Human Body, Environmental Science

The Rusting Metal Mystery - Chemistry Detective Activity | Corrosion, Oxidation

Created by
TWFScience

Turn your students into science detectives with this NO PREP, engaging, real-world investigation focused on chemical change and corrosion. In this case file activity, students analyze rusting observations, examine environmental conditions, interpret moisture and oxygen effects, evaluate corrosion pa

6th - 10th Chemistry, General Science, Physical Science

NGSS MS-PS1-1, MS-PS1-2, MS-PS1-3+3

Also included in: Science Detective Mystery Bundle | Chemistry, Human Body, Environmental Science

Agriculture & Fertilizer Runoff Reading | Grade 8 & Up | Nutrient Cycles, Urban

Created by
TWFScience

Agriculture & Fertilizer Runoff: Causes, Ecological Impacts, and Solutions Reading Comprehension Passage and QuestionsThis reading explores the real-world environmental issue of fertilizer runoff and how human activities on land can impact water systems far beyond where they begin. It is a high-

8th - 12th Earth Sciences, Environment, General Science

Also included in: Human Impact & Sustainability - 13 Reading Comprehension Bundle | Grade 8 and Up

Rare Earth Elements and Technology Reading | Grade 8 & Up | Mining, Resources

Created by
TWFScience

Rare Earth Elements and Technology: Uses, Supply Risks, and Sustainable Solutions Reading Comprehension Passage and QuestionsThis reading explores the critical role rare earth elements play in modern technology and the growing challenges tied to their supply and environmental impact. It is a high-in

8th - 12th Chemistry, Earth Sciences, General Science

The Consequences of Sleep Deprivation Reading | Grade 8 & Up | Circadian Rhythm

Created by
TWFScience

The Consequences of Sleep Deprivation: Health, Learning, and Society Reading Comprehension Passage and QuestionsThis reading explores the real-world science behind sleep deprivation and how it affects the brain, body, and everyday life. It is a high-interest topic that helps students understand why

8th - 12th Biology, General Science, Other (Science)

Also included in: Science Reading Comprehension Article Mega Bundle | Grade 8 and Up

The Case of the Corroded Bike Rack - Physical and Chemical Change Investigation

Created by
TWFScience

Engage your students with this NO PREP, real-world science WHODUNNIT investigation focused on chemical change, rusting, and corrosion. In this structured investigation, students examine real-world conditions, analyze data tables, evaluate the effects of moisture and salt, eliminate possible causes,

7th - 10th Chemistry, General Science, Physical Science

NGSS MS-PS1-1, MS-PS1-2, MS-PS1-5

The Case of the Foggy Classroom Windows - Physical & Chemical Change Activity

Created by
TWFScience

Engage your students with this NO PREP, real-world science WHODUNNIT investigation focused on condensation and phase changes.In this structured investigation, students examine real-world conditions, analyze data tables, evaluate temperature and humidity changes, eliminate possible causes, and constr

7th - 10th Chemistry, General Science, Physical Science

NGSS MS-PS1-1, MS-PS1-2, MS-PS1-5+1

The Water Purification Mystery - Chemistry Detective Activity | Treatment

Created by
TWFScience

Turn your students into science detectives with this NO PREP, engaging, real-world investigation focused on water purification and treatment systems. In this case file activity, students analyze water quality data, examine filtration results, evaluate settling processes, investigate chemical treatme

6th - 10th Chemistry, General Science, Physical Science

NGSS MS-PS1-1, MS-PS1-2, MS-PS1-3+3

Also included in: Science Detective Mystery Bundle | Chemistry, Human Body, Environmental Science

The Case of the Shrinking Balloon - Physical & Chemical Change Activity

Created by
TWFScience

Engage your students with this NO PREP, real-world science WHODUNNIT investigation focused on gas behavior and temperature changes.In this structured investigation, students examine real-world conditions, analyze data tables, evaluate temperature changes, eliminate possible causes, and construct a s

7th - 10th Chemistry, General Science, Physical Science

NGSS MS-PS1-1, MS-PS1-2, MS-PS1-5+1