Biology Handouts

The Foodborne Illness Outbreak Mystery – Detective SUB PLAN | Salmonella

Created by
TWFScience

Turn your students into science detectives with this NO PREP, engaging, real-world investigation focused on foodborne illness and digestive system infection. In this case file activity, students analyze medical data, examine laboratory test results, track pathogen pathways, rank possible causes, and

7th - 11th Anatomy, Biology, General Science

NGSS MS-LS1-1, MS-LS1-2, MS-LS1-3+4

Also included in: Science Detective Mystery Bundle | Chemistry, Human Body, Environmental Science

The Musculoskeletal System Injury Mystery – Detective SUB PLAN | Bones, Tendons

Created by
TWFScience

Turn your students into science detectives with this NO PREP, engaging, real-world investigation focused on musculoskeletal system injuries and movement breakdown. In this case file activity, students analyze strength test data, examine range-of-motion measurements, investigate posture assessments,

7th - 11th Anatomy, Biology, General Science

NGSS MS-LS1-1, MS-LS1-2, MS-LS1-3+4

Also included in: Science Detective Mystery Bundle | Chemistry, Human Body, Environmental Science

The Nutrition & Diet Health Mystery – Detective SUB PLAN | Vitamins, Minerals

Created by
TWFScience

Turn your students into science detectives with this NO PREP, engaging, real-world investigation focused on nutrition, diet, and whole-body health balance. In this case file activity, students analyze medical data, examine laboratory test results, track nutrient pathways, rank possible causes, and b

7th - 11th Anatomy, Biology, General Science

NGSS MS-LS1-1, MS-LS1-2, MS-LS1-3+4

Also included in: Science Detective Mystery Bundle | Chemistry, Human Body, Environmental Science

The Sleep Deprivation Health Mystery – Detective SUB PLAN | Circadian Rhythm

Created by
TWFScience

Turn your students into science detectives with this NO PREP, engaging, real-world investigation focused on sleep deprivation and whole-body health disruption. In this case file activity, students analyze sleep logs, examine laboratory test results, track hormone pathways, rank possible causes, and

7th - 11th Anatomy, Biology, General Science

NGSS MS-LS1-1, MS-LS1-2, MS-LS1-3+4

Also included in: Science Detective Mystery Bundle | Chemistry, Human Body, Environmental Science

The Autoimmune Disorder Mystery – Detective SUB PLAN | Immunity, Body Systems

Created by
TWFScience

Turn your students into science detectives with this NO PREP, engaging, real-world investigation focused on immune system malfunction and autoimmune disorders. In this case file activity, students analyze laboratory data, examine inflammatory markers, evaluate antibody test results, track immune pat

7th - 11th Anatomy, Biology, General Science

NGSS MS-LS1-1, MS-LS1-2, MS-LS1-3+4

Also included in: Science Detective Mystery Bundle | Chemistry, Human Body, Environmental Science

The Blood Types Mystery – Detective SUB PLAN | ABO, Rh factor, Body Systems

Created by
TWFScience

Create a classroom full of science detectives with this NO PREP, engaging, real-world investigation focused on blood types, transfusion compatibility, and immune system response. In this case file activity, students analyze laboratory results, examine transfusion reactions, track antibody pathways,

7th - 11th Anatomy, Biology, General Science

NGSS MS-LS1-1, MS-LS1-2, MS-LS1-3+4

Also included in: Science Detective Mystery Bundle | Chemistry, Human Body, Environmental Science

The Dehydration & Electrolyte Imbalance Mystery – Detective SUB PLAN

Created by
TWFScience

Turn your students into science detectives with this NO PREP, engaging, real-world investigation focused on hydration, electrolyte balance, and whole-body system stability. In this case file activity, students analyze medical data, examine laboratory test results, track fluid and electrolyte pathway

7th - 11th Anatomy, Biology, General Science

NGSS MS-LS1-1, MS-LS1-2, MS-LS1-3+4

Also included in: Science Detective Mystery Bundle | Chemistry, Human Body, Environmental Science

The Immune System Breakdown Mystery – Detective SUB PLAN | Body Systems

Created by
TWFScience

Turn your students into science detectives with this NO PREP, engaging, real-world investigation focused on immune system breakdown and whole-body health disruption. In this case file activity, students analyze laboratory reports, examine white blood cell counts, track stress hormone patterns, evalu

7th - 11th Anatomy, Biology, General Science

NGSS MS-LS1-1, MS-LS1-2, MS-LS1-3+4

Also included in: Science Detective Mystery Bundle | Chemistry, Human Body, Environmental Science

The Screen Time Addiction & Mental Health Mystery – Detective SUB PLAN |

Created by
TWFScience

Turn your students into science detectives with this NO PREP, engaging, real-world investigation focused on screen time addiction and mental health disruption. In this case file activity, students analyze daily screen use data, examine dopamine reward responses, track sleep hormone disruption, evalu

7th - 11th Anatomy, Biology, General Science

NGSS MS-LS1-1, MS-LS1-2, MS-LS1-3+4

Also included in: Science Detective Mystery Bundle | Chemistry, Human Body, Environmental Science

Germ Theory Reading - Germs and the Immune System, Disease | 6th, 7th, 8th Grade

Created by
TWFScience

This grade 6–8 reading comprehension article and questions introduces students to germ theory—the scientific discovery that microorganisms cause many diseases. Students explore how this idea revolutionized medicine, changed hygiene practices, and continues to shape public health today. From the work

6th - 8th Anatomy, Biology, General Science

NGSS MS-LS1-2, MS-LS1-3

Also included in: Reading Comprehension Article & Question Mega Bundle | 6th, 7th, 8th Grade

Disease Spread & Public Health Data Graphing Labs | 6th, 7th, 8th Grade Science

Created by
TWFScience

These three disease spread and public health data graphing activities will help your students understand how infectious diseases spread and how prevention strategies impact public health while building strong graphing and data analysis skills. This bundle gives teachers an easy, NO PREP way to have

6th - 9th Graphing, Biology, General Science

NGSS MS-ESS2-1, MS-ESS2-2, MS-ESS2-3

Also included in: Middle School Science Graphing & Data Analysis Bundle | Real-World Data 6, 7, 8

Spring Environmental Data Graphing Lab Bundle | 6th, 7th, 8th Grade | Seasons

Created by
TWFScience

These three spring environmental change data graphing activities will help your students understand how seasonal climate conditions influence ecosystems while building strong graphing and data analysis skills. This bundle gives teachers an easy, NO PREP way to have students work with real-world envi

6th - 9th Graphing, Biology, General Science

NGSS MS-ESS2-1, MS-ESS2-4, MS-ESS2-6

Also included in: Middle School Science Graphing & Data Analysis Bundle | Real-World Data 6, 7, 8

Energy Transfer and Heat Investigation Graphing Lab Bundle | 6th, 7th, 8th Grade

Created by
TWFScience

These three energy transfer and heat graphing investigations help students understand how thermal energy moves through matter while building strong graphing and data analysis skills. This bundle gives teachers an easy, NO PREP way to have students work with real-world style datasets to explore Heati

6th - 9th Graphing, Biology, General Science

NGSS MS-PS3-3, MS-PS3-4

Also included in: Middle School Science Graphing & Data Analysis Bundle | Real-World Data 6, 7, 8

Design a Habitat & Ecosystem Project | 6th, 7th, 8th Grade

Created by
TWFScience

In this project, your students will explore how habitats support life and how organisms are specially adapted to survive in different environments. Students will design their own habitat, create 10 unique organisms with specific adaptations, and investigate how living and non-living factors interact

7th - 9th Biology, Earth Sciences, Environment

NGSS MS-PS2-1, MS-PS2-3

Population Ecology Data Graphing Lab Bundle | 6th, 7th, 8th Population Dynamics

Created by
TWFScience

These three population ecology data graphing activities will help your students understand how predator and prey populations change over time, how resources affect carrying capacity, and how limiting factors such as food availability and disturbance affect population size while building strong graph

6th - 9th Graphing, Biology, Environment

NGSS MS-LS2-1, MS-LS2-2, MS-LS2-3+5

Also included in: Middle School Science Graphing & Data Analysis Bundle | Real-World Data 6, 7, 8

Human Body Systems Data Graphing Lab Bundle 6th, 7th, 8th Grade | Heart Rate

Created by
TWFScience

These three human body systems data graphing activities will help your students understand how heart rate changes during exercise, how breathing rate and oxygen use increase with activity, and how food energy and activity level are connected while building strong graphing and data analysis skills. T

6th - 9th Graphing, Biology, General Science

NGSS MS-LS1-3

Also included in: Human Body Systems - 5E Lesson Bundle | Cells, Tissues, Organs, Organ Systems

Infectious Disease Data Analysis & Public Health Graphing Bundle | HIGH SCHOOL

Created by
TWFScience

These three disease spread and public health data graphing activities will help your students understand how infectious diseases spread and how prevention strategies impact public health while building strong graphing and data analysis skills. This bundle gives teachers an easy, NO PREP way to have

9th - 12th Graphing, Biology, General Science

NGSS HS-LS1-1, HS-ETS1-2, HS-ETS1-3+1

Also included in: High School Science Graphing and Data Analysis Mega Bundle | Real-World Data Lab

Thermal Energy & Heat Transfer Data Graphing Lab Bundle | HIGH SCHOOL

Created by
TWFScience

These three energy transfer and heat graphing investigations help students understand how thermal energy moves through matter while building strong graphing and data analysis skills. This bundle gives teachers an easy, NO PREP way to have students work with real-world style datasets to explore Heati

9th - 12th Graphing, Biology, General Science

NGSS HS-PS3-1, HS-PS3-2, HS-PS3-4

Also included in: High School Science Graphing and Data Analysis Mega Bundle | Real-World Data Lab

Ecosystem Roles Cipher Puzzle - Ecology Activity | Producers, Consumers

Created by
TWFScience

Looking for a fun way to review ecosystem roles, food chains, and organism interactions? This Ecosystem Roles Cipher Puzzle gives students a no-prep way to practice identifying how different organisms function in ecosystems such as forests, oceans, grasslands, deserts, and ponds.Students read each c

6th - 9th Biology, Earth Sciences, Environment

NGSS MS-LS2-1, MS-LS2-2, MS-LS2-3+2

Also included in: Ecology Concepts Cipher Puzzle Bundle | Ecosystems, Food Webs, Energy Pyramids

Energy Pyramid Levels Cipher Puzzle - Ecology Activity | Trophic Levels, Energy

Created by
TWFScience

Looking for a fun, no-prep way to review energy pyramids, trophic levels, and energy flow in ecosystems? This Energy Pyramid Levels Cipher Puzzle gives students an engaging way to practice identifying where producers, primary consumers, secondary consumers, tertiary consumers, and top predators belo

6th - 9th Biology, Earth Sciences, Environment

NGSS MS-LS2-1, MS-LS2-2, MS-LS2-3+2

Also included in: Ecology Concepts Cipher Puzzle Bundle | Ecosystems, Food Webs, Energy Pyramids

Food Chain and Food Web Cipher Puzzle - Ecology Activity | Ecology Energy Flow

Created by
TWFScience

Looking for a fun, no-prep way to review food chains, food webs, and ecosystem vocabulary? This Food Chain and Food Web Vocabulary Cipher Puzzle gives students an engaging way to practice important ecology terms while decoding a hidden message.Students read each clue, identify the correct vocabulary

6th - 9th Biology, Earth Sciences, Environment

NGSS MS-LS2-1, MS-LS2-2, MS-LS2-3+4

Also included in: Food Chains and Food Webs Worksheet Bundle + Energy Flow in Ecosystems Lesson

Human Impact on Food Webs Cipher Puzzle - Ecology Activity | Overfishing Habitat

Created by
TWFScience

Looking for a fun, no-prep way to review how human activities affect food chains, food webs, and energy flow? This Human Impact on Food Webs Cipher Puzzle gives students an engaging way to practice identifying how overfishing, pollution, habitat loss, pesticide use, and climate change can disrupt ec

6th - 9th Biology, Earth Sciences, Environment

NGSS MS-LS2-1, MS-LS2-2, MS-LS2-3+4

Also included in: Food Chains and Food Webs Worksheet Bundle + Energy Flow in Ecosystems Lesson

Introductory Cellular Respiration Cipher Puzzle - Ecology Activity | ATP, Energy

Created by
TWFScience

Looking for a fun, no-prep way to review the basics of cellular respiration? This Introduction to Cellular Respiration Cipher Puzzle gives students an engaging way to practice key vocabulary and concepts related to how cells release energy from food.Students read each clue, identify the correct cell

6th - 9th Biology, Earth Sciences, Environment

NGSS MS-LS2-1, MS-LS2-2, MS-LS2-3+4

Also included in: Ecology Concepts Cipher Puzzle Bundle | Ecosystems, Food Webs, Energy Pyramids

Human Body Systems & Physiology Data Graphing Lab Bundle | HIGH SCHOOL

Created by
TWFScience

These three human body systems data graphing activities will help your students understand how heart rate changes during exercise, how breathing rate and oxygen use increase with activity, and how food energy and activity level are connected while building strong graphing and data analysis skills. T

9th - 12th Graphing, Biology, General Science

NGSS HS-LS1-2, HS-LS1-3, HS-LS1-7

Also included in: High School Science Graphing and Data Analysis Mega Bundle | Real-World Data Lab