11th Grade Biology Resources

The Antibiotic Resistance Mystery – Detective SUB PLAN | Bacteria, Germ Theory

Created by
TWFScience

The Antibiotic Resistance Mystery - Turn your students into science detectives with this engaging, real-world investigation focused on antibiotic resistance and what happens when bacterial infections no longer respond to treatment. In this case file activity, students analyze medical and laboratory

7th - 11th Anatomy, Biology, General Science

NGSS MS-LS1-1, MS-LS1-2, MS-LS1-3+4

Also included in: Science Detective Mystery Bundle | Chemistry, Human Body, Environmental Science

The Oxygen Delivery Crisis Mystery – Detective SUB PLAN | Human Body System

Created by
TWFScience

The Oxygen Delivery Crisis Mystery – Turn your students into science detectives with this engaging, real-world investigation focused on oxygen delivery in the human body and what happens when oxygen fails to reach cells efficiently—even when breathing appears normal. In this case file activity, stud

7th - 11th Anatomy, Biology, General Science

NGSS MS-LS1-1, MS-LS1-2, MS-LS1-3+4

Also included in: Science Detective Mystery Bundle | Chemistry, Human Body, Environmental Science

The Substance Abuse Impact on Body Systems Mystery – Detective SUB PLAN Activity

Created by
TWFScience

The Substance Abuse & Impact on Body Systems Mystery – Turn your students into science detectives with this engaging, real-world investigation focused on substance use and how vaping, smoking, and alcohol affect multiple body systems. In this case file activity, students analyze medical and labo

7th - 11th Anatomy, Biology, General Science

NGSS MS-LS1-1, MS-LS1-2, MS-LS1-3+4

Also included in: Science Detective Mystery Bundle | Chemistry, Human Body, Environmental Science

Human Body Systems and Health Detective Mystery Bundle | Activity SUB PLAN

Created by
TWFScience

Build a high-engagement, low-prep human body system and health program that grows with you. This bundle collects my Human Body Systems and Health Detective Mystery Case Files—each one built around real-world body system and health problem, evidence analysis, pathway tracking, suspect ranking, and Cl

7th - 11th Anatomy, Biology, General Science

Earth Day Countdown | 22 Environmental Science Starter Slides | Earth Day Warmup

Created by
TWFScience

Earth Day Countdown – Class Starter Discussion Slides & Teacher Guide. 22 Days of Discussion and Collaboration. Fully editable.Looking for an engaging way to spark meaningful conversations about environmental issues leading up to Earth Day or just how humans impact the environment? This Earth Da

6th - 11th Biology, Earth Sciences, Marine Science

NGSS MS-LS2-1, MS-LS2-4, MS-ESS3-1+9

Earth Day Countdown | Environmental Class Starter 3-DAY SAMPLE

Created by
TWFScience

Earth Day Countdown SAMPLE – Class Starter Discussion Slides & Teacher Guide. 3 Days of Discussion and Collaboration. The full version - Earth Day Countdown | 22 Environmental Class Starter Slides for Discussion and Collaboration can be found by clicking here.The full version contains 22, fully

6th - 11th Biology, Earth Sciences, Marine Science

NGSS MS-LS2-1, MS-LS2-4, MS-ESS3-1+9

The Blood Sugar Balance Mystery – Detective SUB PLAN | Insulin, Cells, Pancreas

Created by
TWFScience

Turn your students into science detectives with this NO PREP, engaging, real-world investigation focused on health and blood glucose balance. In this case file activity, students analyze medical data, examine laboratory test results, track hormone pathways, interrogate suspects, and build a scientif

7th - 11th Anatomy, Biology, General Science

NGSS MS-LS1-1, MS-LS1-2, MS-LS1-3+4

Also included in: Science Detective Mystery Bundle | Chemistry, Human Body, Environmental Science

The Foodborne Illness Outbreak Mystery – Detective SUB PLAN | Salmonella

Created by
TWFScience

Turn your students into science detectives with this NO PREP, engaging, real-world investigation focused on foodborne illness and digestive system infection. In this case file activity, students analyze medical data, examine laboratory test results, track pathogen pathways, rank possible causes, and

7th - 11th Anatomy, Biology, General Science

NGSS MS-LS1-1, MS-LS1-2, MS-LS1-3+4

Also included in: Science Detective Mystery Bundle | Chemistry, Human Body, Environmental Science

The Musculoskeletal System Injury Mystery – Detective SUB PLAN | Bones, Tendons

Created by
TWFScience

Turn your students into science detectives with this NO PREP, engaging, real-world investigation focused on musculoskeletal system injuries and movement breakdown. In this case file activity, students analyze strength test data, examine range-of-motion measurements, investigate posture assessments,

7th - 11th Anatomy, Biology, General Science

NGSS MS-LS1-1, MS-LS1-2, MS-LS1-3+4

Also included in: Science Detective Mystery Bundle | Chemistry, Human Body, Environmental Science

The Nutrition & Diet Health Mystery – Detective SUB PLAN | Vitamins, Minerals

Created by
TWFScience

Turn your students into science detectives with this NO PREP, engaging, real-world investigation focused on nutrition, diet, and whole-body health balance. In this case file activity, students analyze medical data, examine laboratory test results, track nutrient pathways, rank possible causes, and b

7th - 11th Anatomy, Biology, General Science

NGSS MS-LS1-1, MS-LS1-2, MS-LS1-3+4

Also included in: Science Detective Mystery Bundle | Chemistry, Human Body, Environmental Science

The Sleep Deprivation Health Mystery – Detective SUB PLAN | Circadian Rhythm

Created by
TWFScience

Turn your students into science detectives with this NO PREP, engaging, real-world investigation focused on sleep deprivation and whole-body health disruption. In this case file activity, students analyze sleep logs, examine laboratory test results, track hormone pathways, rank possible causes, and

7th - 11th Anatomy, Biology, General Science

NGSS MS-LS1-1, MS-LS1-2, MS-LS1-3+4

Also included in: Science Detective Mystery Bundle | Chemistry, Human Body, Environmental Science

The Autoimmune Disorder Mystery – Detective SUB PLAN | Immunity, Body Systems

Created by
TWFScience

Turn your students into science detectives with this NO PREP, engaging, real-world investigation focused on immune system malfunction and autoimmune disorders. In this case file activity, students analyze laboratory data, examine inflammatory markers, evaluate antibody test results, track immune pat

7th - 11th Anatomy, Biology, General Science

NGSS MS-LS1-1, MS-LS1-2, MS-LS1-3+4

Also included in: Science Detective Mystery Bundle | Chemistry, Human Body, Environmental Science

The Blood Types Mystery – Detective SUB PLAN | ABO, Rh factor, Body Systems

Created by
TWFScience

Create a classroom full of science detectives with this NO PREP, engaging, real-world investigation focused on blood types, transfusion compatibility, and immune system response. In this case file activity, students analyze laboratory results, examine transfusion reactions, track antibody pathways,

7th - 11th Anatomy, Biology, General Science

NGSS MS-LS1-1, MS-LS1-2, MS-LS1-3+4

Also included in: Science Detective Mystery Bundle | Chemistry, Human Body, Environmental Science

The Dehydration & Electrolyte Imbalance Mystery – Detective SUB PLAN

Created by
TWFScience

Turn your students into science detectives with this NO PREP, engaging, real-world investigation focused on hydration, electrolyte balance, and whole-body system stability. In this case file activity, students analyze medical data, examine laboratory test results, track fluid and electrolyte pathway

7th - 11th Anatomy, Biology, General Science

NGSS MS-LS1-1, MS-LS1-2, MS-LS1-3+4

Also included in: Science Detective Mystery Bundle | Chemistry, Human Body, Environmental Science

The Immune System Breakdown Mystery – Detective SUB PLAN | Body Systems

Created by
TWFScience

Turn your students into science detectives with this NO PREP, engaging, real-world investigation focused on immune system breakdown and whole-body health disruption. In this case file activity, students analyze laboratory reports, examine white blood cell counts, track stress hormone patterns, evalu

7th - 11th Anatomy, Biology, General Science

NGSS MS-LS1-1, MS-LS1-2, MS-LS1-3+4

Also included in: Science Detective Mystery Bundle | Chemistry, Human Body, Environmental Science

The Screen Time Addiction & Mental Health Mystery – Detective SUB PLAN |

Created by
TWFScience

Turn your students into science detectives with this NO PREP, engaging, real-world investigation focused on screen time addiction and mental health disruption. In this case file activity, students analyze daily screen use data, examine dopamine reward responses, track sleep hormone disruption, evalu

7th - 11th Anatomy, Biology, General Science

NGSS MS-LS1-1, MS-LS1-2, MS-LS1-3+4

Also included in: Science Detective Mystery Bundle | Chemistry, Human Body, Environmental Science

The Consequences of Sleep Deprivation Reading | Grade 8 & Up | Circadian Rhythm

Created by
TWFScience

The Consequences of Sleep Deprivation: Health, Learning, and Society Reading Comprehension Passage and QuestionsThis reading explores the real-world science behind sleep deprivation and how it affects the brain, body, and everyday life. It is a high-interest topic that helps students understand why

8th - 12th Biology, General Science, Other (Science)

Also included in: Science Reading Comprehension Article Mega Bundle | Grade 8 and Up

Antibiotic Resistance Reading | How Bacteria Evolve and Adapt | Grade 8 & Up

Created by
TWFScience

Antibiotic Resistance: Causes, Consequences, and Global Responses Reading Comprehension Passage and QuestionsThis reading explores the real-world science behind antibiotic resistance and how it impacts human health, healthcare systems, and global society. It is a high-interest topic that helps stude

8th - 12th Basic Principles, Biology, General Science

NGSS HS-LS4-1, HS-LS4-2, HS-LS4-3+2

Also included in: Science Reading Comprehension Article Mega Bundle | Grade 8 and Up

Water Pollution and Public Health Reading | Grade 8 & Up | Ecosystem Damage

Created by
TWFScience

Water Pollution: Sources, Health Risks, Ecosystem Damage, and Solutions Reading Comprehension Passage and QuestionsThis reading explores the real-world science behind water pollution and how it affects ecosystems, human health, and society. It helps students understand how pollutants enter water sys

8th - 12th Biology, Earth Sciences, Environment

NGSS MS-LS2-1, MS-LS2-4, MS-ESS3-1+7

Also included in: Human Impact & Sustainability - 13 Reading Comprehension Bundle | Grade 8 and Up

Deforestation and Habitat Destruction Reading | Grade 8 & Up | Biodiversity

Created by
TWFScience

Deforestation and Habitat Destruction Reading Comprehension Passage and QuestionsThis reading explores the real-world science behind deforestation and habitat destruction and how they affect biodiversity, climate, water systems, and human communities. It helps students understand why forests and oth

8th - 12th Biology, Earth Sciences, Environment

NGSS MS-LS2-1, MS-LS2-4, MS-ESS3-1+7

Also included in: Human Impact & Sustainability - 13 Reading Comprehension Bundle | Grade 8 and Up

Genetics, Heredity, DNA, and Traits - 5E Lesson Bundle | Genotype and Phenotype

Created by
TWFScience

Genetics, Heredity, DNA, and Traits - Fully editable and Complete 5E Lesson. This bundle is designed for science students in grades 10–11, but the content can be adapted to fit different learning levels.Lesson Objectives:Throughout this 5E lesson, students will learn about:Genetics and heredityInher

9th - 12th Science, Biology, General Science

NGSS HS-LS1-1, HS-LS1-2

Science Detective Mystery Bundle | Chemistry, Human Body, Environmental Science

Created by
TWFScience

This growing bundle of bundles is composed of high-engagement, no-prep Science Detective Mystery activities that grow with you. This bundle consists of mystery activities that examine real-world chemistry, human body systems and health, environmental science, and space exploration topics and guide y

7th - 11th Biology, Chemistry, Physical Science

NGSS MS-PS1-1, MS-PS1-2, MS-PS1-4+2

Macromolecules and Biomolecules 5E Lesson | Carbohydrates, Lipids, Proteins

Created by
TWFScience

Macromolecules and Biomolecules - Fully editable and Complete 5E Lesson. This bundle is designed for biology and biochemistry students studying macromolecules, biomolecules, carbon chemistry, carbohydrates, lipids, proteins, nucleic acids, and the biomolecules that make up living things. The content

10th - 12th Science, Biology, General Science

NGSS HS-LS1-1, HS-LS1-5, HS-LS1-6

How Humans Negatively Impact the Environment Reading | Grade 8 and Up

Created by
TWFScience

This reading helps students explore the many ways human activities harm the environment and how those problems are connected. Students learn about climate change, greenhouse gases, coral bleaching, deforestation, biodiversity loss, air and water pollution, nutrient pollution, plastic waste, overfish

8th - 12th Biology, Earth Sciences, Environment

NGSS MS-LS2-1, MS-LS2-2, MS-LS2-3+8

Also included in: Science Reading Comprehension Article Mega Bundle | Grade 8 and Up